Every cell in our body contains a set of instructions called our genetic code. This genetic code is largely the same between individuals, however every individual has small differences called genetic variants. Some genetic variants predispose us to developing common and rare diseases. A polygenic risk score combines millions of genetic variants to determine an individual's risk of developing a given disease.
We analyze individuals with a disease and those without a disease to find which variations in DNA are associated with the disease. We then calculate a score for a new individual based on how many of those variations they have.
The accuracy of the PRS in predicting an individual's risk varies depending on the disease. For some diseases, genetics plays a large role in determining risk while for other diseases, factors such as environmental exposure to chemicals, lifestyle patterns and behavior plays a significant role.
In the case of autism, a large population-based study showed that individuals in the top 10% of our PRS score have a 2.8- fold increased odds of developing autism compared to those in the bottom 10% of scores.
The PRS test will help parents understand their child's genetic risk for developing autism and aids in tailoring our monitoring service to the child's needs.
Cheek (buccal) swabs may cause minor irritation to the inside of your child's cheek. However, this is very rare and does not require treatment. Clear instructions on how to perform the cheek swab are included in your test kit.
We currently do not accept insurance.
The test, while incredibly valuable, is only one part of our multi-pronged approach for early autism detection. We do not sell the PRS test alone.
The Neurona Health PRS test is designed to predict a child's genetic predisposition forr developing autism. If your child has already been diagnosed with autism this test will not be useful. However if you have more children or have relatives with children it may be useful in determining their genetic risk for developing autism.
While our PRS test can help quantify your child's genetic risk of autism, our test is NOT a diagnostic test for autism. Some children with a high polygenic risk score will not develop autism, while some children with a low polygenic risk score will develop autism.
It means they are at a higher genetic risk for developing autism than the average individual. A large population-based study showed that individuals in the top 10% of our PRS score have a 2.8- fold increased odds of developing autism compared to those in the bottom 10% of scores.
It means that they are more likely to develop autism when compared to the average individual. Our test cannot definitely predict whether a given individual will develop autism.
All genomic data will be stored in HIPAA compliant data storage.
We will never sell genetic data/patient data at any time.
Please reach out to us via the Contact Us feature on our website and we will provide your child's raw genetic data.
Many pediatric cases of autism are missed every year, with some estimates as high as 25% of cases. Our service provides specialized clinician-driven autism screening to monitor for signs of developing autism. Numerous scientific studies show early detection and intervention leads to remarkably better outcomes for children with autism
We offer telehealth visits with Board-Certified-Behavioral Analysts (BCBAs) during high risk developmental time periods determined by our team of expert physicians and scientists.
A BCBA is a Board Certified Behavior Analyst trained in providing Applied Behavioral Analysis. During our monitoring sessions, they will assess your child for developmental delays or signs of autism.
A BCBA cannot diagnose autism but they are trained to look for signs of autism
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